Author

V. Kharchenko

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Assay:protein structure· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

L. Jaremko· 2 shared P. Mandal· 2 shared A. Radhakrishnan· 1 shared B. E. Black· 1 shared C. Liao· 1 shared D. Bensaddek· 1 shared F. Huser· 1 shared J. Li· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBiophysics

L. Jaremko

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Author profile →

3 papers

Recent·Most cited

Zinc ions prevent a-synuclein aggregation by enhancingchaperone function of human serum albumin

S. Al-Harthi, V. Kharchenko, P. Mandal, S. Gourdoupis, L. Jaremko

The paper investigates how zinc ions enhance the anti-aggregation chaperone function of human serum albumin on alpha-synuclein.

bioRxiv · Jul 4, 2022Biophysics

Molecular basis of UHRF1 allosteric activation for synergistic histone modification binding by PI5P

P. Mandal, Z. Yerkesh, V. Kharchenko, L. Zandarashvili, D. Bensaddek, L. Jaremko, B. E. Black, W. Fischle

This study identifies how PI5P allosterically activates UHRF1 to synergistically bind H3unmodified and H3K9me3 histone marks through conformational changes.

bioRxiv · Aug 4, 2021 · PreprintBiochemistry

Molecular Basis for the Adaptive Evolution of Environment Sensing by H-NS Proteins

X. Zhao, V. Kharchenko, U. F. Shahul Hameed, C. Liao, F. Huser, J. M. Remington, A. Radhakrishnan, M. Jaremko, Łukasz Jaremko, S. T. Arold, J. Li

This study investigates how H-NS proteins evolved to sense environmental changes by comparing orthologs from different bacteria and using biophysical methods to reveal electrostatic interactions involved in adaptation.

bioRxiv · Apr 21, 2020Biochemistry