NADK upregulation is an essential metabolic adaptation that enables breast cancer metastatic colonization
D. Ilter, T. Schild, N. Ward, S. Drapela, E. Adhikari, V. Low, E. Le-Lau, G. M. DeNicola, M. McReynolds, A. P. Gomes
This study identifies NADK upregulation as a critical metabolic adaptation enabling breast cancer metastasis by enhancing NADPH production and oxidative stress resistance.
bioRxiv · Mar 25, 2022 · PreprintCancer Biology