Author

D. Broekaert

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:experimental assay· 1

Frequent Co-Authors

J. Fernandez-Garcia· 3 shared S.-M. Fendt· 3 shared D. Lambrechts· 2 shared I. Vermeire· 2 shared J. Van Elsen· 2 shared M. Planque· 2 shared A. A. Pane· 1 shared A. Ahmed· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

J. Fernandez-Garcia

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation

P. Altea-Manzano, G. Doglioni, A. M. Cuadros, E. Nolan, J. Fernandez-Garcia, Q. Wu, F. Cidre-Aranaz, A. Montagne, M. Planque, O. Marin-Bejar, J. Van Elsen, I. Vermeire, D. Broekaert, C. Riera-Domingo, F. Richard, , S.-M. Fendt

This study identifies palmitate-rich metastatic niches as promoters of metastasis by enhancing p65 acetylation and NF-κB signaling in breast cancer cells.

bioRxiv · Oct 24, 2022Cancer Biology

CD8+ T Cell Metabolic Rewiring Defined by Single-Cell RNA-Sequencing Identifies a Critical Role of ASNS Expression Dynamics in T Cell Differentiation

J. Fernandez-Garcia, F. Franco, S. Parik, A. A. Pane, D. Broekaert, J. Van Elsen, I. Vermeire, T. Van Brussel, R. Schepers, E. Modave, T. Karakach, P. Carmeliet, D. Lambrechts, P.-C. Ho, S.-M. Fendt

This study uses scRNA-seq to analyze CD8+ T cell metabolic dynamics during activation and differentiation, identifying ASNS expression dynamics as critical for determining T cell fate.

bioRxiv · Jul 27, 2021Immunology

Age-induced methylmalonic acid accumulation promotes tumor progression and aggressiveness

A. P. Gomes, D. Ilter, V. Low, J. Endress, J. Fernandez-Garcia, A. Rosenzweig, T. Schild, D. Broekaert, A. Ahmed, M. Planque, I. Elia, J. Han, C. Kinzig, E. Mullarky, A. Mutvei, , J. Blenis

The paper shows that methylmalonic acid accumulation with age promotes tumor progression by inducing SOX4 and reprogramming cancer cells.

bioRxiv · Jun 4, 2020 · PreprintCancer Biology