A. P. Gomes

This study shows that chemotherapy-induced senescence-associated secretome promotes metastasis in ovarian cancer by reprogramming metabolism and increasing cell detachment.

This study uses a mathematical model to show that ploidy and resource availability in the tumor microenvironment influence glioblastoma initiation and recurrence.

This study identifies Pik3c3 as a vulnerability in dormancy-prone breast cancer cells, showing its inhibition reduces metastasis in preclinical models.

This study identifies NADK upregulation as a critical metabolic adaptation enabling breast cancer metastasis by enhancing NADPH production and oxidative stress resistance.

This paper demonstrates that CD5L reduces sepsis severity by both anti-bacterial and anti-inflammatory mechanisms, showing therapeutic potential in mouse models.

The paper shows that methylmalonic acid accumulation with age promotes tumor progression by inducing SOX4 and reprogramming cancer cells.