BiochemistryJournal of Medicinal ChemistryPeer-reviewed
Discovery of First-in-Class PROTAC Degraders of SARS-CoV-2 Main Protease
Y. R. Alugubelli, J. Xiao, K. Khatua…·S. Xu
This paper develops first-in-class PROTAC degraders of SARS-CoV-2 main protease, showing they reduce MPro levels and exhibit anti-SARS-CoV-2 activity.
DOI 10.1021/acs.jmedchem.3c02416