Author

V. Roudko

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Assay:flow cytometry· 1

Frequent Co-Authors

N. Bhardwaj· 2 shared A. Baccarini· 1 shared A. Bektesevic· 1 shared A. H. Rahman· 1 shared A. O. Kamphorst· 1 shared A. Wroblewska· 1 shared B. Cubitt· 1 shared B. D. Brown· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersImmunology

N. Bhardwaj

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Author profile →

3 papers

Recent·Most cited

Functional impairment of "helpless" CD8+ memory T cells is transient and driven by prolonged but finite cognate antigen presentation

V. van der Heide, B. Davenport, B. Cubitt, V. Roudko, D. Choo, E. Humblin, K. Jhun, K. Angeliadis, T. Dawson, G. Furtado, A. O. Kamphorst, R. Ahmed, J. C. de la Torre, D. Homann

This study shows that helpless CD8+ memory T cells, which form without CD4+ help, have transient functional impairments due to prolonged antigen exposure, which resolve over time.

bioRxiv · Jan 22, 2024Immunology

Perturb-map enables CRISPR genomics with spatial resolution and identifies regulators of tumor immune composition

M. Dhainaut, S. A. Rose, G. Akturk, A. Wroblewska, E. Sook Park, S. R. Nielsen, M. Buckup, V. Roudko, L. Pia, J. Le Berichel, A. Bektesevic, B. H. Lee, A. Baccarini, N. Bhardwaj, A. H. Rahman, , B. D. Brown

Perturb-map enables spatial CRISPR screening in tumors, identifying genes that regulate immune composition by mapping gene knockouts and their effects on the tumor microenvironment.

bioRxiv · Jul 13, 2021 · PreprintImmunology

Widespread immunogenic poly-epitope frameshift mutations in microsatellite unstable tumors

V. Roudko, C. Cimen Bozkus, T. Orfanelli, S. V. Blank, B. Greenbaum, N. Bhardwaj

The paper identifies immunogenic poly-epitope frameshift mutations in MSI-H tumors and validates their potential for off-the-shelf cancer vaccines.

bioRxiv · Jun 12, 2019 · PreprintCancer Biology