Cell BiologybioRxiv
Transient non-integrative nuclear reprogramming promotes multifaceted reversal of aging in human cells
T. J. Sarkar, M. Quarta, S. Mukherjee…·V. Sebastiano
This study shows that transient non-integrative nuclear reprogramming reverses aging in human cells by rejuvenating epigenetic clocks and cellular functions without losing identity.
DOI 10.1038/s41467-020-15174-3