V. See

Inhibition of glioblastoma cell proliferation and invasion by the choline-kinase inhibitor JAS239 varies with cell type and hypoxia

This study evaluates how hypoxia affects the efficacy of the ChoK inhibitor JAS239 in GBM cells, showing variable responses across cell lines and metabolic pathway changes.

Comparison between optical tissue clearing methods for detecting administered mesenchymal stromal cells in mouse lungs

This study compares optical tissue clearing methods to detect mesenchymal stromal cells in mouse lungs, finding that CUBIC enables direct imaging of fluorescently labeled MSCs and their interaction with host cells.

Oxygen-dependent changes in HIF binding partners and post-translational modifications regulate stability and transcriptional activity

The paper investigates how oxygen levels affect HIF-1 and HIF-2 stability and activity through post-translational modifications and interactions, identifying novel oxygen-dependent PTMs and regulatory roles.

USP29 is a novel non-canonical Hypoxia Inducible Factor-α activator

This study identifies USP29 as a non-canonical activator of HIF-α that stabilizes HIF-1 and HIF-2 independently of oxygen, PHD, and pVHL, and correlates with disease progression in prostate cancer.

Downregulation of both mismatch repair and non-homologous end-joining pathways in hypoxic brain tumour cell lines

This study examines how hypoxia affects DNA repair gene expression in glioblastoma cell lines, finding downregulation of mismatch repair and non-homologous end-joining pathways.

4D imaging and analysis of multicellular tumour spheroid cell migration and invasion

This study uses 4D imaging to analyze 3D cell migration and invasion in glioblastoma spheroids, evaluating chemotherapy efficacy on invasion.

CDK inhibitors reduce cell proliferation and reverse hypoxia-induced metastasis of neuroblastoma tumours in a chick embryo model

Magnetic resonance imaging for characterization of a chick embryo model of cancer cell metastases

This study uses MRI with contrast agents to detect metastatic neuroblastoma in a chick embryo model, showing its effectiveness compared to fluorescence methods.