The deubiquitylase USP31 controls the Chromosomal Passenger Complex and spindle dynamics
E. Bertsoulaki, H. L. Glover, J. I. Gomes-Neto, B. Pizer, H. Maiato, S. Urbe, M. J. Clague
This study identifies USP31 as a deubiquitylase regulating the chromosomal passenger complex and spindle dynamics during mitosis, leading to chromosomal segregation errors and polyploidy upon depletion.
bioRxiv · Aug 17, 2022 · PreprintCell Biology