BiophysicsbioRxivPreprint
Catalytically inactive dKbCas12d guided by sgRNA and new insights into its binding through a single-molecule approach
Aleksandr Andreevich Alekseev, Valerii Klimko, Marina Abramova…·Anatolii Arseniev
The paper describes modifications to the CRISPR-Cas12d system, identifies catalytically inactive variants, and demonstrates their high specificity using single-molecule techniques.
DOI 10.1101/2023.12.12.571249