Cancer BiologybioRxivPreprint
Opioids trigger breast cancer metastasis through E-Cadherin downregulation and STAT3 activation promoting epithelial mesenchymal transition
Sabrina Tripolt, Vanessa M. Knab, Heidi A. Neubauer…·Daniela A. Fux
This study shows opioids promote breast cancer metastasis by reducing E-Cadherin and activating STAT3, leading to epithelial-mesenchymal transition.