KSHV upregulates the long non-coding RNA PURPL via p73 to suppress p53
Samia Showgan, Diana Meary, Guy Journo…·Meir Shamay
This study shows KSHV upregulates the oncogenic lncRNA PURPL through p73 to suppress p53, promoting PEL cell proliferation.
Author
Bar-Ilan University
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
Samia Showgan, Diana Meary, Guy Journo…·Meir Shamay
This study shows KSHV upregulates the oncogenic lncRNA PURPL through p73 to suppress p53, promoting PEL cell proliferation.
Supriya Bhattacharya, Nilabja Roy Chowdhury, Anuj Ahuja…·Meir Shamay
This study shows that LINE-1 retrotransposons are upregulated in KSHV-infected cells and their knockdown impairs proliferation and alters gene expression.
Nilabja Roy Chowdhury, Vyacheslav Gurevich, Meir Shamay
This study identifies constitutive and lytically induced enhancers in the KSHV genome using functional assays and CRISPR techniques, revealing a 'viral super-enhancer' that regulates latency-to-lytic transition.
Baruh Polis, Kolluru D. Srikanth, Vyacheslav Gurevich…·Abraham O. Samson
The paper investigates the effect of arginase inhibition with norvaline on adult neurogenesis in Alzheimer's disease mice, finding increased neuronal survival and molecular markers of maturation.
Baruh Polis, Kolluru D. Srikanth, Vyacheslav Gurevich…·Abraham O. Samson
This study evaluates L-norvaline's neuroprotective effects in an AD mouse model, finding it reverses cognitive decline and reduces beta-amyloidosis and microgliosis.