Author

W. Arap

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Approach:deep learning· 1 Organism:mouse· 1 Assay:protein sequence· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Assay:structural biology· 1

Frequent Co-Authors

C. Markosian· 3 shared R. Pasqualini· 3 shared S. K. Burley· 3 shared D. I. Staquicini· 2 shared F. H. F. Tang· 2 shared J. N. Onuchic· 2 shared P. C. Whitford· 2 shared S. K. Libutti· 2 shared

Activity by Year

2021-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMicrobiology

C. Markosian

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Structural models of SARS-CoV-2 Omicron variant in complex with ACE2 receptor or antibodies suggest altered binding interfaces

J. H. Lubin, C. Markosian, D. Balamurugan, R. Pasqualini, W. Arap, S. K. Burley, S. D. Khare

The paper generates structural models of the SARS-CoV-2 Omicron variant bound to ACE2 and antibodies, revealing altered binding interfaces and neutralization escape mechanisms.

bioRxiv · Dec 12, 2021Biophysics

Apropos of Universal Epitope Discovery for COVID-19 Vaccines: A Framework for Targeted Phage Display-Based Delivery and Integration of New Evaluation Tools

C. Markosian, D. I. Staquicini, P. Dogra, E. Dodero-Rojas, F. H. F. Tang, T. L. Smith, V. G. Contessoto, S. K. Libutti, Z. Wang, V. Cristini, P. C. Whitford, S. K. Burley, J. N. Onuchic, R. Pasqualini, W. Arap

The paper describes a framework using targeted phage display to identify conserved epitopes on the SARS-CoV-2 Spike protein for universal vaccine development.

bioRxiv · Aug 30, 2021Microbiology

Design and proof-of-concept for targeted phage-based COVID-19 vaccination strategies with a streamlined cold-free supply chain

D. I. Staquicini, F. H. F. Tang, C. Markosian, V. J. Yao, F. I. Staquicini, E. Dodero Rojas, V. G. Contessoto, D. Davis, P. O'Brien, N. Habib, T. L. Smith, N. Bruiners, R. L. Sidman, M. L. Gennaro, E. C. Lattime, , R. Pasqualini

This paper designs and evaluates phage-based and AAVP-based vaccination strategies for SARS-CoV-2 that induce systemic antibody responses in mice, with potential for a cold-free supply chain.

bioRxiv · Mar 15, 2021Microbiology