W. Jahnen-Dechent

This paper introduces a cryo-to-liquid phase correlative light/electron microscopy workflow to overcome limitations of graphene liquid cells and enables imaging of biological processes.

This study shows fetuin-A deficiency leads to microvascular calcification and premature aging in mice, associated with thrombosis and fibrosis rather than osteochondrogenic differentiation.

The paper identifies fetuin-A, pyrophosphate, and magnesium as key regulators of calcification in fetuin-A deficient mice and shows that their combined deficiency can be mitigated by dietary or parenteral supplementation.