C. Schmitz

Dsg2 truncation causes a lethal barrier breakdown in mice

This study shows that a DSG2 mutation causing Dsg2 truncation leads to a lethal intestinal barrier defect and a skewed IL17 response in mice, similar to Crohn's disease.

Unveiling the Molecular Mechanisms of the Type-IX Secretion System's Response Regulator: Structural and Functional Insights

This study characterizes PorX, a response regulator in the Type-IX secretion system, revealing its unique enzymatic activity and zinc-dependent dimerization, with implications for virulence factor secretion in bacterial pathogens.

New, biomechanically sound tendon tissue after injection of uncultured, autologous, adipose derived regenerative cells in partial Achilles tendon defects in rabbits

This study injects uncultured autologous adipose-derived regenerative cells into rabbit Achilles tendon defects and finds improved biomechanical properties compared to sham treatment.

Synergism and phytotoxicity: the effects of tank-mix additives on the biological efficacy of Cu2+ against Venturia inaequalis and Podosphaera leucotricha

This study evaluates how three tank-mix additives affect the biological efficacy and phytotoxicity of copper formulations against two fungal pathogens in apple crops.

CD300lf conditional knockout mouse reveals strain-specific cellular tropism for murine norovirus

This study uses a Cd300lf conditional knockout mouse to show that CD300lf on tuft cells is essential for persistent MNoVCR6 infection, while myelomonocytic cells are major targets for non-persistent MNoVCW3, with STAT1 restricting its tropism.

A formin-mediated cell wall- plasma membrane- cytoskeleton continuum is required for symbiotic infections in Medicago truncatula

This study identifies SYFO1, a formin protein in Medicago truncatula, which connects the cell wall and cytoskeleton to facilitate rhizobial infection by enabling plasma membrane remodeling and cell polarization.

Microvasculopathy And Soft Tissue Calcification In Mice Are Governed by Fetuin-A, Pyrophosphate And Magnesium

The paper identifies fetuin-A, pyrophosphate, and magnesium as key regulators of calcification in fetuin-A deficient mice and shows that their combined deficiency can be mitigated by dietary or parenteral supplementation.

COLLECTIVE AGGRESSIVENESS LIMITS COLONY PERSISTENCE IN HIGH BUT NOT LOW ELEVATION SITES IN AMAZONIAN SOCIAL SPIDERS

The paper examines how collective aggressiveness in social spider colonies affects their persistence at different elevation sites in the Amazon, finding that less aggressive colonies persist better at high elevations.

Exposure of zebra mussels to extracorporeal shock waves demonstrates formation of new mineralized tissue inside and outside the focus zone

This study shows that zebra mussels exposed to extracorporeal shock waves develop new mineralized tissue both inside and outside the treatment zone.