CRISPR-Cas9 interrogation of a putative fetal globin repressor in human erythroid cells.
Jennifer E. Chung, Wendy Magis, Jonathan T. Vu…·Mark A. DeWitt
This study uses CRISPR-Cas9 to test a putative fetal globin repressor region, finding it does not autonomously silence gamma-globin, suggesting it is not a therapeutic target for beta-hemoglobinopathies.