ImmunologybioRxivPreprint
Development of a Novel CD4+ TCR Transgenic Line that Reveals a Dominant Role for CD8+ DC and CD40-Signaling in the Generation of Helper and CTL Responses to Blood Stage Malaria
Daniel Fernandez-Ruiz, Lei Shong Lau, Nazanin Ghazanfari…·William R Heath
This paper develops a CD4+ TCR transgenic mouse line to study helper and CTL responses to blood-stage malaria, showing CD8+ DC and CD40-signaling are critical for immunity.
DOI 10.1101/113837