Cell BiologybioRxivPreprint
An ancient transcription factor functions as the master regulator of primary cilia formation
Weihua Wang, Xiqi Zhang, Yi Qiu…·Zhangfeng Hu
This study identifies Xap5 as a master regulator of primary cilia formation by interacting with Nono to activate Sox5 and Sox9, revealing a conserved transcriptional network involved in ciliary diversity.
DOI 10.1101/2025.11.28.691250