Author

Zhangfeng Hu

Institute of Microalgae Synthetic Biology and Green Manufacturing, School of Life Sciences, Jianghan UniversityORCID 0000-0002-4841-8073Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Approach:genetic perturbation / CRISPR· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Junqiao Xing· 3 shared Cheng Xu· 2 shared Haochen JiangiD· 2 shared Hongni LiuiD· 2 shared Weihua WangiD· 2 shared Xiqi Zhang· 2 shared Aijie Tian· 1 shared Guangmei TianiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersCell Biology

Junqiao Xing

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintNov 28, 2025

An ancient transcription factor functions as the master regulator of primary cilia formation

Weihua Wang, Xiqi Zhang, Yi Qiu…·Zhangfeng Hu

This study identifies Xap5 as a master regulator of primary cilia formation by interacting with Nono to activate Sox5 and Sox9, revealing a conserved transcriptional network involved in ciliary diversity.

DOI 10.1101/2025.11.28.691250

mousebulk RNA-seq

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Synthetic BiologybioRxivPreprintSep 25, 2025

Expression screening and functional verification of recombinant hirudin from novel chassis cell Chlamydomonas reinhardtii

Li Feng, Junqiao Xing, Aijie Tian…·Zhangfeng Hu

This paper produces functional hirudin in Chlamydomonas reinhardtii, demonstrating high thrombin-inhibitory activity and safety in a murine model.

DOI 10.1101/2025.09.25.678210

mouseexperimental assay

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Cell BiologybioRxivJan 1, 2024

Control of ciliary transcriptional programs during spermatogenesis by antagonistic transcription factors

Weihua Wang, Junqiao Xing, Xiqi Zhang…·Zhangfeng Hu

This study identifies XAP5 and XAP5L as antagonistic transcription factors that regulate ciliary gene expression during spermatogenesis, with XAP5 promoting and XAP5L inhibiting ciliary transcription factors at different stages.

DOI 10.7554/elife.94754.3

mousebulk RNA-seq

𝕏 PostBluesky