Author

Xiaozhong Bao

National Cancer Institute

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Cancer Biology· 1

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

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David LevensiD· 1 shared John M. SedivyiD· 1 shared Kris YlayaiD· 1 shared Stefania PittalugaiD· 1 shared Stephen M. HewittiD· 1 shared Subhendu DasiD· 1 shared Susan MackemiD· 1 shared Svetlana J. Pack· 1 shared

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2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

David LevensORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintJul 28, 2025

A tumorigenesis threshold for endogenous Myc revealed by dosage-compensation for Myc haploinsufficiency in the absence of p53.

Xiaozhong Bao, Zied Abdullaev, Subhendu Das…·David Levens

This study shows that reducing endogenous Myc levels in p53-deficient mice extends tumor-free survival and that tumors compensate by increasing Myc dosage or expression.

DOI 10.1101/2025.07.28.667174

mouseexperimental assay

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