Author

Y. Chander

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 7

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:host-pathogen & immune response· 6 Organism:chicken / avian· 4 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Assay:metagenomics· 1 Assay:proteomics· 1

Frequent Co-Authors

N. Khandelwal· 7 shared N. Kumar· 7 shared S. Barua· 7 shared B. N. Tripathi· 6 shared R. Kumar· 6 shared T. Riyesh· 5 shared Y. Pal· 4 shared A. Verma· 3 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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7 shared papersMicrobiology

N. Khandelwal

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Author profile →

7 papers

Recent·Most cited

p38-MAPK is prerequisite for the synthesis of SARS-CoV-2 protein

P. Mittal, N. Khandelwal, Y. Chander, A. Verma, R. Kumar, C. Putatunda, S. Barua, B. R. Gulati, N. Kumar

This study shows that p38-MAPK is essential for SARS-CoV-2 replication, as its inhibition reduces viral growth and its activation supports RNA/protein synthesis without affecting viral entry or budding.

bioRxiv · Sep 27, 2023Microbiology

Evaluation of the safety, immunogenicity and efficacy of a new live-attenuated lumpy skin disease vaccine in India

N. Kumar, S. Barua, R. Kumar, N. Khandelwal, A. Kumar, A. Verma, L. Singh, B. Godara, Y. Chander, T. Riyesh, D. K. Sharma, A. Pathak, S. Kumar, R. K. Dedar, V. Mehta, , B. N. Tripathi

This study evaluates a new live-attenuated LSD vaccine, showing it is safe, immunogenic, and effective in protecting cattle against LSD with high seroconversion rates.

bioRxiv · Dec 10, 2022Microbiology

hnRNPA1 regulates early translation to replication switch in SARS-CoV-2 life cycle

R. Kumar, Y. Chander, N. Khandelwal, H. Nagori, A. Verma, Y. Pal, B. R. Gulati, B. N. Tripathi, S. Barua, N. Kumar

This study shows that SARS-CoV-2 RNA methylation, mediated by hnRNPA1, regulates the switch from translation to replication in the viral life cycle.

bioRxiv · Jul 13, 2021 · PreprintMicrobiology

Emetine as an antiviral agent suppresses SARS-CoV-2 replication by inhibiting interaction of viral mRNA with eIF4E: An in vitro study

R. Kumar, N. Khandelwal, Y. Chander, T. Riyesh, B. R. Gulati, Y. Pal, B. N. Tripathi, S. Barua, N. Kumar

This study shows emetine inhibits SARS-CoV-2 replication by blocking viral RNA interaction with eIF4E and demonstrates its antiviral activity against SARS-CoV-2 and IBV in vitro.

bioRxiv · Nov 29, 2020Microbiology

Isolation and characterization of lumpy skin disease virus from cattle in India

N. Kumar, Y. Chander, R. Kumar, N. Khandelwal, T. Riyesh, K. Chaudhary, K. Shanmugasundaram, S. Kumar, A. Kumar, M. K. Gupta, Y. Pal, S. Barua, B. N. Tripathi

This study isolates and characterizes Lumpy Skin Disease Virus (LSDV) from cattle in India, showing it is closely related to Kenyan strains and demonstrating alternative cell lines for virus isolation and propagation.

bioRxiv · Oct 8, 2020Microbiology

Isolation and characterization of bovine herpes virus 5 (BHV5) from cattle in India

N. Kumar, Y. Chander, T. Riyesh, N. Khandelwal, R. Kumar, H. Kumar, B. N. Tripathi, S. Barua

The paper reports the first isolation of BHV5 from aborted cattle in India and confirms its identity through molecular and serological methods.

bioRxiv · Jan 24, 2020Microbiology

Inhibitor of sarco/endoplasmic reticulum calcium-ATPase impairs paramyxovirus replication

N. Kumar, S. Barua, B. N. Tripathi, N. Khandelwal, T. Riyesh, R. D. Krishan, R. K. Jangir, Y. Chander, K. K. Chaubey, S. V. Singh

This study shows that SERCA inhibition reduces paramyxovirus replication and that viruses can develop resistance to this inhibition.

bioRxiv · May 23, 2018Microbiology