Cancer BiologybioRxivPreprint
Nanopore sequencing methods detect cell-free DNA associated with minimal residual disease and central nervous system infiltration in pediatric Acute Lymphoblastic Leukemia
S. Sampathi, Y. Chernyavskaya, M. Haney…·J. Blackburn
This paper develops a nanopore sequencing method to detect B-ALL-associated cell-free DNA in blood and CSF, enabling early detection of MRD and CNS infiltration in pediatric ALL patients.
DOI 10.1101/2021.09.27.462067