BiophysicsbioRxiv
Structural insights into the modes of relaxin-binding and tethered-agonist activation of RXFP1 and RXFP2
A. Sethi, S. Bruell, T. Ryan…·P. R. Gooley
The paper identifies a conserved motif critical for RXFP1 and RXFP2 activation, showing distinct structural roles in receptor activity.
DOI 10.1016/j.jmb.2021.167217