Author

T. Ryan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

J. A. Boyce· 2 shared M. Gutierrez-Arcelus· 2 shared M. Lee· 2 shared N. Bhattacharyya· 2 shared T. M. Laidlaw· 2 shared X. Wang· 2 shared A. Maxfield· 1 shared A. Ray· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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2 shared papersImmunology

J. A. Boyce

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Increased epithelial mTORC1 activity in chronic rhinosinusitis with nasal polyps

N. A. Barrett, G. X. Huang, N. R. Hallen, M. Lee, K. Zheng, X. Wang, M. V. Mandanas, S. Djeddi, D. Fernandez, J. Hacker, T. Ryan, R. W. Bergmark, N. Bhattacharyya, S. Lee, A. Z. Maxfield, , M. Gutierrez-Arcelus

The paper identifies increased mTORC1 activity in CRSwNP epithelial cells and links it to cytokine production and inflammation in both CRSwNP and asthma.

bioRxiv · Oct 13, 2023 · PreprintImmunology

Type 2 Inflammation Drives an Airway Basal Stem Cell Program Through Insulin Receptor Substrate Signaling

X. Wang, N. Hallen, M. Lee, S. Samuchiwal, Q. Ye, K. Buchheit, A. Maxfield, R. Roditi, R. Bergmark, N. Bhattacharyya, T. Ryan, D. Gakpo, S. Raychaudhuri, D. Dwyer, T. M. Laidlaw, , N. Barrett

This study identifies BCAM as a marker of airway basal stem cells and shows that T2 cytokines drive their expansion via IRS signaling in CRSwNP.

bioRxiv · Oct 13, 2022Immunology

Structural insights into the modes of relaxin-binding and tethered-agonist activation of RXFP1 and RXFP2

A. Sethi, S. Bruell, T. Ryan, F. Yan, M. H. Tanipour, Y. F. Mok, C. D. Joyce, Y. Khandokar, R. D. Metcalfe, M. D. W. Griffin, D. J. Scott, M. A. Hossain, E. J. Petrie, R. A. D. Bathgate, P. R. Gooley

The paper identifies a conserved motif critical for RXFP1 and RXFP2 activation, showing distinct structural roles in receptor activity.

bioRxiv · Jun 6, 2021Biophysics