Author

Y. Furuike

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Research Focus:chromatin & epigenetic regulation· 3 Approach:experimental assay· 3 Assay:protein structure· 2 Approach:biophysical modeling· 1 Organism:C. elegans· 1 Research Focus:development & morphogenesis· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

S. Akiyama· 4 shared A. Mukaiyama· 3 shared D. Ouyang· 3 shared D. Simon· 2 shared E. Yamashita· 2 shared K. Ito-Miwa· 2 shared S. Saito· 2 shared T. Kondo· 2 shared

Activity by Year

2021-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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4 shared papersBiochemistry

S. Akiyama

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Author profile →

4 papers

Recent·Most cited

The priming phosphorylation of KaiC is activated by the release of its autokinase autoinhibition

Y. Furuike, Y. Onoue, S. Saito, T. Mori, S. Akiyama

This study identifies the autoinhibition mechanism of KaiC priming phosphorylation and shows how KaiA relieves this inhibition by altering R385 interactions.

bioRxiv · Mar 21, 2024Biochemistry

Regulation Mechanisms of the Dual ATPase in KaiC

Y. Furuike, A. Mukaiyama, S.-i. Koda, D. Simon, D. Ouyang, K. Ito-Miwa, S. Saito, E. Yamashita, T. Nishiwaki-Ohkawa, K. Terauchi, T. Kondo, S. Akiyama

This study investigates how the dual ATPase activities in KaiC coordinate to regulate the cyanobacterial circadian clock through structural and biochemical analysis.

bioRxiv · Oct 28, 2021Biochemistry

Elucidation of Master Allostery Essential for Circadian Clock Oscillation in Cyanobacteria

Y. Furuike, A. Mukaiyama, D. Ouyang, K. Ito-Miwa, D. Simon, E. Yamashita, T. Kondo, S. Akiyama

The paper identifies the structural basis for allostery in the cyanobacterial circadian clock by analyzing KaiC protein states and shows how coupling between a phospho-switch and ATPase activity drives oscillation.

bioRxiv · Aug 30, 2021Biophysics

Cross-scale Analysis of Temperature Compensation in the Cyanobacterial Circadian Clock System

Y. Furuike, D. Ouyang, T. Tominaga, T. Matsuo, A. Mukaiyama, Y. Kawakita, S. Fujiwara, S. Akiyama

The paper investigates temperature compensation in the cyanobacterial circadian clock by analyzing KaiC dynamics using quasielastic neutron scattering and mutation studies.

bioRxiv · Aug 20, 2021Biophysics