Author

D. Ouyang

Princeton University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Biophysics· 2 Biochemistry· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell signaling & trafficking· 4 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:development & morphogenesis· 2 Assay:imaging· 2 Research Focus:protein folding & dynamics· 2 Assay:protein structure· 2 Approach:biophysical modeling· 1

Frequent Co-Authors

A. Mukaiyama· 3 shared S. Akiyama· 3 shared Y. Furuike· 3 shared D. Simon· 2 shared E. Yamashita· 2 shared K. Ito-Miwa· 2 shared T. Kondo· 2 shared A. Abid· 1 shared

Activity by Year

2019-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersBiophysics

A. Mukaiyama

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Cell cycle-dependent transitions in PCP protein mobility erase and restore planar cell polarity in mitosis

D. Ouyang, Lena P. Basta, P. Sil, B.W. Joyce, Eszter Pósfai, Danelle Devenport

The paper shows PCP proteins transition between mobile and stable states during mitosis, losing and restoring planar cell polarity through lateral diffusion and adhesive interactions.

bioRxiv · Jan 12, 2026 · PreprintCell Biology

Dual Ethanolamine Head Groups in Ionizable Lipids Facilitate Phospholipid-free Stable Nanoparticle Formulation for Augmented and Safer mRNA Delivery

J. Lu, T. Jiang, X. Li, S. Tan, Y. Zhang, H. Gu, L. Chen, J. Guo, R. Yu, J. Zang, D. Ouyang, H. Yu, H. Yao, M. Qiu, J. Lin

This paper introduces ionizable lipids with dual ethanolamine head groups for phospholipid-free mRNA delivery, showing improved stability, efficiency, and reduced toxicity.

bioRxiv · Oct 13, 2023 · PreprintBioengineering

Regulation Mechanisms of the Dual ATPase in KaiC

Y. Furuike, A. Mukaiyama, S.-i. Koda, D. Simon, D. Ouyang, K. Ito-Miwa, S. Saito, E. Yamashita, T. Nishiwaki-Ohkawa, K. Terauchi, T. Kondo, S. Akiyama

This study investigates how the dual ATPase activities in KaiC coordinate to regulate the cyanobacterial circadian clock through structural and biochemical analysis.

bioRxiv · Oct 28, 2021Biochemistry

Elucidation of Master Allostery Essential for Circadian Clock Oscillation in Cyanobacteria

Y. Furuike, A. Mukaiyama, D. Ouyang, K. Ito-Miwa, D. Simon, E. Yamashita, T. Kondo, S. Akiyama

The paper identifies the structural basis for allostery in the cyanobacterial circadian clock by analyzing KaiC protein states and shows how coupling between a phospho-switch and ATPase activity drives oscillation.

bioRxiv · Aug 30, 2021Biophysics

Cross-scale Analysis of Temperature Compensation in the Cyanobacterial Circadian Clock System

Y. Furuike, D. Ouyang, T. Tominaga, T. Matsuo, A. Mukaiyama, Y. Kawakita, S. Fujiwara, S. Akiyama

The paper investigates temperature compensation in the cyanobacterial circadian clock by analyzing KaiC dynamics using quasielastic neutron scattering and mutation studies.

bioRxiv · Aug 20, 2021Biophysics

Deep Learning Interpretation of Echocardiograms

A. Ghorbani, D. Ouyang, A. Abid, B. He, J. H. Chen, R. A. Harrington, D. H. Liang, E. A. Ashley, J. Y. Zou

This paper applies deep learning to echocardiograms to identify cardiac structures, estimate function, and predict systemic phenotypes, showing high accuracy in key metrics.

bioRxiv · Jun 24, 2019Bioengineering

Blood cells of adult Drosophila do not expand, but control survival after bacterial infection by induction of Drosocin around their reservoir at the respiratory epithelia

P. Sanchez Bosch, K. Makhijani, L. Herboso, K. S. Gold, R. Baginsky, K. J. Woodcock, B. Alexander, K. Kukar, S. Corcoran, D. Ouyang, C. Wong, E. J. Ramond, C. Rhiner, E. Moreno, B. Lemaitre, , K. Brueckner

The paper identifies the largest reservoir of blood cells in adult Drosophila and shows they control survival after bacterial infection by inducing Drosocin expression in surrounding tissues.

bioRxiv · Mar 16, 2019 · PreprintImmunology