Author

D. Simon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Microbiology· 2 Biochemistry· 1 Bioengineering· 1 Biophysics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:cell signaling & trafficking· 4 Research Focus:cell type annotation· 3 Assay:protein structure· 2 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Organism:C. elegans· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. Mukaiyama· 2 shared D. Ouyang· 2 shared E. Yamashita· 2 shared K. Ito-Miwa· 2 shared S. Akiyama· 2 shared T. Kondo· 2 shared Y. Furuike· 2 shared Z. Takats· 2 shared

Activity by Year

2019-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersBiochemistry

A. Mukaiyama

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Controlling lipid droplet dynamics via tether condensates

C. Amari, D. Simon, T. Bellon, M.-A. Plamont, A.-R. Thiam, Z. Gueroui

This paper introduces ControLD, a method to control lipid droplet dynamics by sequestering and releasing them via engineered condensates, showing that isolation impairs their remobilization during metabolic needs.

bioRxiv · May 15, 2024Cell Biology

Human Placenta-Derived Mesenchymal Stem Cells Stimulate Neuronal Regeneration By Promoting Axon Growth And Restoring Neuronal Activity

P. de la Villa, M. T. Moreno, M. Mellen, M. Iglesias, D. Simon, E. H. de Laorden, J. Sierra

This study demonstrates that human placenta-derived mesenchymal stem cells promote axon growth and restore neuronal activity in damaged rat-retina neurons through paracrine mechanisms involving neurotrophic factors.

bioRxiv · Oct 26, 2023 · PreprintCell Biology

Laser Desorption Rapid Evaporative Ionisation Mass Spectrometry (LD-REIMS) demonstrates a direct impact of hypochlorous acid stress on PQS-mediated quorum sensing in Pseudomonas aeruginosa

R. Bradley, D. Simon, L. Spiga, Y. Xiang, Z. Takats, H. D. Williams

This paper uses LD-REIMS to show HOCl stress reduces PQS quorum sensing and virulence factors in P. aeruginosa.

bioRxiv · Oct 11, 2023 · PreprintMicrobiology

Fiberbots: Robotic fibers for high-precision minimally invasive surgery

M. E. M. K. Abdelaziz, J. Zhao, B. M. G. Rosa, H.-T. Lee, D. Simon, K. Vyas, B. Li, H. J. A. Koguna, Y. Li, A. A. Demircali, H. Uvet, G. Gencoglan, A. Akcay, M. Elriedy, J. M. Kinross, , B. Temelkuran

This paper develops robotic fibers (fiberbots) that enable high-precision motion through thermal expansion, demonstrating scalability and integration with medical devices for potential applications in surgery and biomedical engineering.

bioRxiv · Feb 16, 2023Bioengineering

PPAR-γ regulates the effector function of human TH9 cells by promoting glycolysis

N. L. Bertschi, O. Steck, F. Luther, C. Bazzini, L. von Meyenn, A. Felser, I. Keller, O. Friedli, S. Freigang, N. Begre, C. Lamos, M. P. Gabutti, M. Benzaquen, M. Laimer, D. Simon, , C. Schlapbach

This study shows PPAR-γ promotes glycolysis in human TH9 cells, enhancing IL-9 expression and effector function through mTORC1.

bioRxiv · Aug 16, 2022 · PreprintImmunology

Regulation Mechanisms of the Dual ATPase in KaiC

Y. Furuike, A. Mukaiyama, S.-i. Koda, D. Simon, D. Ouyang, K. Ito-Miwa, S. Saito, E. Yamashita, T. Nishiwaki-Ohkawa, K. Terauchi, T. Kondo, S. Akiyama

This study investigates how the dual ATPase activities in KaiC coordinate to regulate the cyanobacterial circadian clock through structural and biochemical analysis.

bioRxiv · Oct 28, 2021Biochemistry

Elucidation of Master Allostery Essential for Circadian Clock Oscillation in Cyanobacteria

Y. Furuike, A. Mukaiyama, D. Ouyang, K. Ito-Miwa, D. Simon, E. Yamashita, T. Kondo, S. Akiyama

The paper identifies the structural basis for allostery in the cyanobacterial circadian clock by analyzing KaiC protein states and shows how coupling between a phospho-switch and ATPase activity drives oscillation.

bioRxiv · Aug 30, 2021Biophysics

Positional dynamics and glycosomal recruitment of developmental regulators during trypanosome differentiation

B. Szoor, D. Simon, F. Rojas, J. Young, D. R. Robinson, T. Kruger, M. Engstler, K. R. Matthews

The paper tracks TbPIP39 recruitment to glycosomes during trypanosome differentiation and identifies a regulatory site coordinating signaling and glycosomal development.

bioRxiv · Apr 10, 2019Microbiology