Cell BiologyAgingPeer-reviewed
Gorlin syndrome-induced pluripotent stem cells form medulloblastoma with loss of heterozygosity in PTCH1
Y. Ikemoto, T. Miyashita, M. Nasu…·A. UMEZAWA
This study shows that Gorlin syndrome patient-derived iPSCs form medulloblastoma in mice, with one tumor showing PTCH1 loss of heterozygosity.
DOI 10.18632/aging.103258