Cancer BiologybioRxiv
MYC regulates ribosome biogenesis and mitochondrial gene expression programs through interaction with Host Cell Factor-1
T. M. Popay, J. Wang, C. M. Adams…·W. Tansey
This study identifies HCF-1 as a critical co-factor for MYC in driving mitochondrial and ribosome biogenesis gene expression, and shows its impact on cell growth and tumor progression.
DOI 10.7554/elife.60191