Cell BiologybioRxiv
Overarching control of autophagy and DNA damage response by CHD6 revealed by modeling a rare human pathology
Y. Kargapolova, R. Rehimi, H. Kayserli…·A. Papantonis
The paper identifies a CHD6 mutation causing Hallermann-Streiff syndrome and shows it disrupts autophagy and DNA damage response through chromatin remodeling.
DOI 10.1038/s41467-021-23327-1