Author

Y. M. Ayala

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Assay:protein structure· 2 Approach:biophysical modeling· 1 Assay:protein sequence· 1

Frequent Co-Authors

A. E. Conicella· 1 shared A. M. D'Ordine· 1 shared E. H. Hemamali· 1 shared G. H. Zerze· 1 shared G. L. Dignon· 1 shared H. B. Schmidt· 1 shared J. Mittal· 1 shared L. D. Mamede· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

A. E. Conicella

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cell BiologybioRxivAug 6, 2023

RNA-mediated ribonucleoprotein assembly controls TDP-43 nuclear retention

P. M. dos Passos, E. H. Hemamali, L. D. Mamede…·Y. M. Ayala

This study shows that RNA-mediated TDP-43 self-assembly forms macromolecular complexes that retain TDP-43 in the nucleus, preventing cytoplasmic aggregation and highlighting potential therapeutic targets.

DOI 10.1371/journal.pbio.3002527

humanprotein structure

𝕏 PostBluesky

BiochemistrybioRxivMay 18, 2019

TDP-43 α-helical structure tunes liquid-liquid phase separation and function

A. E. Conicella, G. L. Dignon, G. H. Zerze…·N. L. Fawzi

This study shows that mutations in TDP-43's helical region modulate its phase separation and function, with implications for ALS and synthetic biology.

DOI 10.1073/pnas.1912055117

humanprotein structure

𝕏 PostBluesky