Cancer BiologybioRxiv
Multiplexed Single-Molecule Epigenetic Analysis of Plasma-Isolated Nucleosomes for Cancer Diagnostics
V. Fedyuk, N. Erez, N. Furth…·E. Shema
The paper develops EPINUC, a single-molecule assay for analyzing plasma nucleosomes to detect cancer with high accuracy, including early-stage colorectal cancer and determining tumor origin.
DOI 10.1038/s41587-022-01447-3