Serine Starvation Silences Estrogen Receptor Signaling through Histone Hypoacetylation
A. M. Li, Y. Li, B. He, Y. Ramirez, H. Jiang, M.-N. Zhou, C. Lu, J. J. Gruber, E. B. Rankin, J. Ye
The paper shows serine starvation reduces ER expression and histone acetylation in breast cancer cells, linking metabolic stress to chromatin changes and ER pathway inactivation.
bioRxiv · Sep 5, 2021 · PreprintCancer Biology