Author

J. J. Gruber

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. M. Li· 1 shared A. M. Lipchik· 1 shared A. Rangarajan· 1 shared B. He· 1 shared B. S. Geller· 1 shared C. Lu· 1 shared E. B. Rankin· 1 shared H. Jiang· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

A. M. Li

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 5, 2021

Serine Starvation Silences Estrogen Receptor Signaling through Histone Hypoacetylation

A. M. Li, Y. Li, B. He…·J. Ye

The paper shows serine starvation reduces ER expression and histone acetylation in breast cancer cells, linking metabolic stress to chromatin changes and ER pathway inactivation.

DOI 10.1101/2021.09.05.459037

humanChIP-seq

𝕏 PostBluesky

BiochemistrybioRxivPreprintJun 25, 2021

An acetyl-click screening platform identifies a small molecule inhibitor of Histone Acetyltransferase 1 (HAT1) with anti-tumor activity

J. J. Gruber, A. Rangarajan, T. Chou…·A. M. Lipchik

This paper identifies a small molecule inhibitor of HAT1, a histone acetyltransferase, showing anti-tumor activity in vitro and in vivo.

DOI 10.1101/2021.06.25.449993

humanproteomics

𝕏 PostBluesky