Author

Y.-C. Lou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

C. Chen· 1 shared C.-H. Wang· 1 shared D.-L. M. Tzou· 1 shared H.-H. Yeh· 1 shared H.-Y. Huang· 1 shared K. J. D. Carillo· 1 shared K. Namba· 1 shared K.-P. Wu· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

C. Chen

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Author profile →

2 papers

Recent·Most cited

Cryo-EM inspired NMR analysis reveals a pH-induced conformational switching mechanism for imparting dynamics to Betanodavirus protrusions

P. Sterbova, C.-H. Wang, K. J. D. Carillo, Y.-C. Lou, T. Kato, K. Namba, D.-L. M. Tzou, W.-H. Chang

This study reveals a pH-induced conformational switching mechanism in Betanodavirus protrusions that governs infectivity through dynamic structural changes.

bioRxiv · Mar 8, 2024 · PreprintBiochemistry

Structural basis of transcriptional activation by the OmpR/PhoB-family response regulator PmrA

Y.-C. Lou, H.-Y. Huang, H.-H. Yeh, W.-H. Chiang, C. Chen, K.-P. Wu

The paper reports a cryo-EM structure of a PmrA-dependent transcription activation complex and shows how PmrA interacts with DNA and RNA polymerase to activate gene transcription.

bioRxiv · Jul 20, 2022 · PreprintBiophysics