Author

Y.-L. Tsai

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Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

A. Weiss· 1 shared B. B. Au-Yeung· 1 shared C. Scharer· 1 shared J. Eggert· 1 shared K. Salaita· 1 shared W. Zinzow-Kramer· 1 shared Y. Hu· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. Weiss

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1 paper

Recent·Most cited

ImmunologybioRxivJan 27, 2023

Accumulation of TCR signaling from self-antigens in naive CD8 T cells mitigates early responsiveness

J. Eggert, W. Zinzow-Kramer, Y. Hu…·B. B. Au-Yeung

The study shows that prolonged TCR signaling from self-antigens in naive CD8 T cells reduces their responsiveness to foreign antigens through gene expression changes and negative regulators like Sts1 and Cbl-b.

DOI 10.1126/scisignal.adh0439

mousebulk RNA-seq

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