BiophysicsbioRxivPreprint
Structure-activity relationships of B.1.617 and other SARS-CoV-2 spike variants
T.-J. Yang, P.-Y. Yu, Y.-C. Chang…·S.-T. D. Hsu
This study reports cryo-EM structures of SARS-CoV-2 spike variants and finds mutations alter conformation and glycan shield, enhance ACE2 binding, but are neutralized by three antibodies.