BiochemistrybioRxiv
A cholesterol switch controls phospholipid scrambling by G protein-coupled receptors
Indu Menon, Taras Sych, Yeeun Son…·Anant K. Menon
The paper shows cholesterol inhibits GPCR-mediated phospholipid scrambling in synthetic vesicles, suggesting a mechanism for maintaining plasma membrane asymmetry.
DOI 10.1016/j.jbc.2024.105649