BioengineeringbioRxivPreprint
Unexplored regions of the protein sequence-structure map revealed at scale by a library of foldtuned language models
A. M. Subramanian, Z. A. Martinez, A. L. Lourenco…·M. Thomson
This paper introduces foldtuning, a method to generate novel protein sequences with target structures, bypassing evolutionary barriers and enabling synthetic biology applications.
DOI 10.1101/2023.12.22.573145