BiophysicsbioRxiv
Template-free detection and classification of heterogeneous membrane-bound complexes in cryo-electron tomograms
A. Martinez-Sanchez, Z. Kochovski, U. Laugks…·V. Lucic
The paper develops a template-free method to detect and classify membrane-bound complexes in cryo-ET data, revealing previously undetected ER translocon species and their structural and spatial characteristics.