BiochemistrybioRxiv
Design Principles for Inflammasome Inhibition by Pyrin-Only-Proteins
Z. Mazanek, S. Wu, G. Belotte…·J. Sohn
This study identifies how pyrin-only-proteins inhibit inflammasomes by targeting different filament assembly steps, revealing their target redundancy and inhibition mechanisms.
DOI 10.7554/elife.81918