BiochemistrybioRxiv
eEF2 kinase enhances the expression of PD-L1 by promoting the translation of its mRNA
C. G. Proud, Y. Wu, J. Xie…·J. Li
This study shows that eEF2K enhances PD-L1 expression by promoting its mRNA translation through a uORF in the 5-UTR, making cancer cells more vulnerable to immune attack.