MicrobiologybioRxivPreprint
A Metabolic Sum Rule Dictates Bacterial Response to Short-Chain Fatty Acid Stress
B. R. Taylor, V. Patsalo, H. Okano…·T. Hwa
The paper identifies a metabolic sum rule in bacteria showing that exogenous metabolite accumulation depletes endogenous metabolites, causing growth reduction, and demonstrates how cells mitigate this by acidifying their cytoplasm.
DOI 10.1101/2022.08.31.506075