Cancer BiologybioRxivPreprint
Reduced glutamate decarboxylase 1 underlies morphine-promoted lung metastasis of triple-negative breast cancer in mice
S. H. Chen, C.-H. Shih, T.-L. Ke…·L. Chen
This study shows that long-term morphine use in mice increases lung metastasis of triple-negative breast cancer by reducing GAD1 and taurine biosynthesis, suggesting taurine may counteract this effect.
DOI 10.1101/2023.09.14.557710