Author

Zhijie Deng

Tisch Cancer Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Jian Jun JiniD· 2 shared Alba Bundo· 1 shared Alicia Yue· 1 shared Changzhong Jin· 1 shared Ernesto GuccioneiD· 1 shared H. Ümit KanıskaniD· 1 shared Hyerin YimiD· 1 shared Julia VeleziD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Jian Jun JinORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMay 6, 2026

Multispecific nanobody degraders co-deplete membrane receptors and enable targeted delivery of diverse payloads

Md Kabir, Yong Joon (Jeffrey) Kim, Zhijie Deng…·Yi Shi

This paper develops MINDS, a multispecific nanobody-Fc platform that co-depletes membrane receptors and delivers diverse payloads, showing improved antitumor activity in cancer models.

DOI 10.64898/2026.05.02.722401

humanproteomics

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BiochemistryJournal of Medicinal ChemistryPeer-reviewedApr 11, 2024

Discovery of the First-in-class G9a/GLP PROTAC Degrader

Julia Velez, Yulin Han, Hyerin Yim…·Jian Jun Jin

This paper discovers a first-in-class PROTAC degrader for G9a/GLP, showing effective degradation and superior anticancer activity compared to existing inhibitors.

22 citations

experimental assaydrug response / drug discovery

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