Molecular BiologyStem Cell ReportsPeer-reviewed
Fibro-Adipogenic Progenitors require autocrine IGF-I in homeostatic and regenerating skeletal muscle
Yangyi E. Luo, Zoe Abe-Teh, Tarek Y. Alsaghir…·Elisabeth R. Barton
This study shows that autocrine IGF-I is essential for FAP function in muscle homeostasis and regeneration, with loss of IGF-I leading to impaired regeneration and altered FAP properties.