Bowen Li

This study identifies locus-specific transposable elements driving VEXAS syndrome pathophysiology by regulating myeloid commitment in UBA1-mutant hematopoietic stem cells.

LUMI-lab autonomously designs ionizable lipids for mRNA delivery, identifying brominated tails and achieving 20.3% gene editing efficacy in mice.

This paper develops a heart-on-a-chip model to study immune-induced cardiac dysfunction, identifying mitochondrial DNA as a key factor and showing therapeutic potential of endothelial exosomes.