Author

Grigorii V. Andrianov

Fox Chase Cancer CenterORCID 0000-0001-5328-4738Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Approach:experimental assay· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

J. L. KaranicolasiD· 3 shared Benjamin E. BlassiD· 1 shared Celina Heier· 1 shared Christopher S Parry· 1 shared Elena Bondarenko· 1 shared Emeline HaroldseniD· 1 shared Erica A. GolemisiD· 1 shared Ezra Shimabenga· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersBiochemistry

J. L. KaranicolasORCID

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3 papers

Recent·Most cited

BiochemistrybioRxivPreprintMay 29, 2026

Rescuing the Function of Missense-Mutated Tumor Suppressor VHL using Stabilizing Small Molecules

Mariam Ahmed Fouad, Christopher S Parry, Sven A. Miller…·John Karanicolas

The paper identifies small molecules that stabilize and restore function to missense-mutated VHL proteins in kidney cancer cells.

DOI 10.64898/2026.01.02.697373

humanproteomics

𝕏 PostBluesky

BioinformaticsInternational Journal of Molecular SciencesPeer-reviewedNov 18, 2024

vScreenML v2.0: Improved Machine Learning Classification for Reducing False Positives in Structure-Based Virtual Screening

Grigorii V. Andrianov, Emeline Haroldsen, John Karanicolas

vScreenML v2.0 improves virtual screening by reducing false positives through a streamlined Python implementation, outperforming existing tools in hit discovery.

3 citations

machine learning (classical)drug response / drug discovery

𝕏 PostBluesky

BiochemistryACS Chemical BiologyPeer-reviewedDec 30, 2023

Novel substrate prediction for the TAM family of RTKs using phosphoproteomics and structure-based modeling

Naomi E. Widstrom, Grigorii V. Andrianov, Jason L. Heier…·Laurie L. Parker

This paper designs synthetic peptide substrates for TAM family kinases using phosphoproteomics and AlphaFold2, showing that predicted interactions correlate with biochemical validation.

2 citations

proteomicsdeep learning

𝕏 PostBluesky