Laurie L. Parker

This study shows sorbate induces lysine sorbylation via Class I HDACs, altering inflammation gene expression without affecting histone acetylation.

The paper develops antibody-free time-resolved terbium luminescence assays for CDK5 and CDK2 using synthetic substrates with phospho-inducible motifs, enabling CDK5-specific drug discovery.

This paper designs synthetic peptide substrates for TAM family kinases using phosphoproteomics and AlphaFold2, showing that predicted interactions correlate with biochemical validation.