Loïc Carrique

This study produces and characterizes recombinant procollagen I variants to elucidate the functional role of the α2(I) chain in fibril formation and proteolytic processing.

The paper determines the structure of PCPE-2 bound to BMP-1, revealing how PCPE-2 inhibits BMP-1 through a bipartite interaction involving its CUB domains.

This study identifies promoter-dependent nuclear export as a mechanism for influenza A virus to select its genome for packaging into virions.

This study characterizes the structure and function of CCHFV RNA-dependent RNA polymerase, revealing its unique features and antiviral susceptibility.

The paper describes the structure and function of a membrane-spanning E3 ubiquitin ligase complex, revealing its role in developmental processes and linking mutations to human birth defects.

The paper introduces Di-Gluebodies, covalently-dimerized nanobodies, to improve cryo-EM structure determination of small proteins by providing rigidity and modularity.

This study shows that Spt5 enhances Xrn2 activity to facilitate Pol II transcription termination and prevent non-coding transcript expression.

This study characterizes the structural and functional interaction between influenza A virus RNA polymerase and host RNA Polymerase II CTD, identifying key residues and their roles in transcription and replication.